I would suggest alternating with ivomec (or Equimax which contains ivomec and a tapeworm wormer) and a pyrantel pamoate medicine like Pro Pam. Safeguard is kinda expensive but you need to use it all along. Ideally, I would use it every 3rd month and use a cheaper wormer like ivomec or pro pam the 2 months in between.
I used panacur paste for 3 days (4 turns on tube adjuster) one month and panacur paste ( same dose) for 3days and on 4th day 1CC ivermectin next month . Had a dog checked by vet , had no worms , not even heart worms . Hope this helps , Big Jim.